
Extended Half-Life IGF-1 Analog · Cell Growth Research · COA Verified
For research and laboratory use only. Not for human consumption. By purchasing, you confirm you are a qualified researcher.
For Research Purposes Only. Not approved for human consumption.
IGF-1 LR3 is a synthetic analog of Insulin-like Growth Factor-1 with a modified sequence that reduces IGFBP binding, extending half-life from ~15 minutes (native IGF-1) to ~20-30 hours. As a downstream mediator of growth hormone, IGF-1 plays central roles in cell growth, differentiation, and survival across virtually every tissue type. The LR3 modification makes it a highly practical research tool for studying systemic IGF-1 effects.
Q: How does IGF-1 LR3 differ from native IGF-1?
A: Reduced IGFBP binding extends half-life from ~15 minutes to ~20-30 hours, allowing sustained IGF-1 receptor activation without the rapid clearance of native IGF-1.
Q: What are the primary research uses?
A: Cell growth signaling, muscle tissue biology, anti-apoptotic mechanisms, and metabolic function including glucose uptake and lipid metabolism.
Q: Storage requirements?
A: Store at -80°C for long-term stability (-20°C acceptable short-term). Avoid repeated freeze-thaw cycles. IGF-1 LR3 is more sensitive to degradation than many peptides.
Related Research: Peptide Research Overview
For laboratory research use only. Not for human consumption. Not evaluated by the FDA.