Melanocortin Receptor Research · COA Verified
For research and laboratory use only. Not for human consumption. By purchasing, you confirm you are a qualified researcher.
For Research Purposes Only. Not approved for human consumption.
PT-141 (Bremelanotide) is a synthetic cyclic peptide analog of alpha-MSH and a metabolite of Melanotan II. It is a non-selective melanocortin receptor agonist with high affinity for MC3R and MC4R, making it valuable for central melanocortin system research. Unlike MT-2, PT-141 has been more selectively studied for its CNS effects rather than peripheral melanocortin actions.
Q: What is the central melanocortin system?
A: A brain-based neuroendocrine system involving MC3R and MC4R receptors in the hypothalamus that regulates energy homeostasis, sexual function, and autonomic outputs.
Q: How does PT-141 differ from MT-2?
A: PT-141 is a more selective CNS-active metabolite of the MT-2 synthetic pathway. Research suggests it has greater CNS penetration and less peripheral melanocortin activity than MT-2.
Q: What receptors does PT-141 activate?
A: Primarily MC3R and MC4R with high affinity. These central melanocortin receptors regulate multiple physiological functions via hypothalamic signaling.
Related Research: MT-2 Research Peptide | KPV (alpha-MSH fragment)
For laboratory research use only. Not for human consumption. Not evaluated by the FDA.
